Robert Knepper (Theodore Bagwell "T-Bag"), Amaury Nolasco (Fernando Sucre), Rockmond Dunbar (Benjamin Miles Franklyn), Sarah Wayne Callies (Dr Sarah Tandcredi), Paul Adelstein (Paul Kellerman), Wade Williams (Bradley Bellick), William Fichtner (Agent Alexander Mahone), Stacy Keach (Henry Pope)
Peter Stormare (John Abruzzi), Silas Weir Mitchell (Charles Patoshik), Lane Garisson (David Apolskis), Marshall Allman (LJ Burrows), Reggie Lee (Bill Kim)
